Titrage

[Saint mom 0]

Voici ce qui a été rapporté via une personne qui a assisté à un séminaire de titrage donné par Jean Dodds.

Citation :

I went to Jean's presentation on vaccinations and it was very
interesting.

She has a canine blood bank for which she keeps 120 greyhounds. She has been using these dogs (as well as other group of dogs) as subjects in testing her vaccination protocol. Basically she gives only distemper, parvo and rabies. Bordetella, adenovirus, and Lyme are given only if the animal has exposure to these diseases and given after 12 weeks of age.

Her recommendation is to start a 9 weeks with a distemper/parvo combo and repeat it at 12 weeks and again at 16-20 weeks. Then boost it again at one year of age. You can start the vaccines at 6 weeks, no earlier, but she does not feel that they are effective. Rabies she recommends after 6 months if possible. Then she titers the dogs every year. She has found adequate titers in dogs that are 10 years post vaccinations. Rather than do the titers you may want to revaccinate every three years until the "animal reaches geriatric age, at which time booster vaccination is likely to be unnecessary and may be unadvisable for those with aging or immunologic disorders."

She also recommends you avoid vaccinating bitches 30-45 before seasons, during their season, pregnancy or lactation.

Here are the reasons to not over vaccinate given at the presentation:

"The onset of adverse reactions to conventional vaccinations (or inciting drugs, chemicals, or infectious agents) can be an immediate hypersensitivity or anaphylactic reaction, or can occur acutely (24-48 hours afterwards), or later on (10-45 days).

In a delayed type immune response often caused by immune-complex formation. Typical signs of adverse immune reactions include fever, stiffness, sore joints and abdominal tenderness, susceptibility to infection, central and peripheral nervous system disorder or inflammation, collapse win autoagglutinated red blood cells and jaundice, or generalized pinpoint hemorrhages or bruises. Liver enzymes may be markedly elevated and liver or kidney failure may accompany bone marrow suppression.

Furthermore, recent vaccination of genetically susceptible breeds has been associated with transient seizure in puppies and adult dogs, as well as a variety of autoimmune diseases including those affecting blood, endocrine organs, joint, skin and mucosa, central nervous system, eyes, muscle, liver, kidneys, and bowel. It is postulated that an underlying genetic predisposition to these conditions places other littermates and close relative at increased risk.

Vaccination of pet and research dogs with polyvalent vaccines containing rabies virus or rabies vaccine alone was recently shown to induce production of antithyroglobulin autoantibodies, a provocative and important finding with implication for the subsequent development of hypothyroidism (Scott-Moncrieff et al, 2002).

Vaccination also can overwhelm the immunocompromised or even healthy host that is repeatedly challenged with other environmental stimuli and is genetically predisposed to react adversely upon viral exposure. The recently weaned young puppy or kitten entering a new environment is at greater risk here, as its relatively immature immune system can be temporarily or more permanently harmed. Consequences in later life may be the increased susceptibility to chronic debilitating diseases.

As combination vaccines contain antigens other than those of the clinically important infectious disease agents, some may be unnecessary; and their use may increase the risk of adverse reactions.

With the exception of a recently introduced multivalent Leptospira
spp. vaccine, the other leptospira vaccines accord little protection
against the clinically important fields strains of leptospirosis, and the
antibodies they elicit typically last only a few months.

Other vaccines, such as for Lyme disease, may not be needed, because the disease is limited to certain geographical areas. Annual revaccination for rabies is required by some states even though there are USDA licensed rabies vaccine with a 3 year duration. Thus, the overall risk-benefit ratio
of using certain vaccines or multiple antigen vaccines given
simultaneously and repeatedly should be reexamined. It must be recognized, however, that we have the luxury of asking such questions today only because the risk of disease has been effectively reduced by the widespread use of vaccination programs."

Jean Dodd's ideas about vaccination have been around for years and now seem to be filtering into the mainstream.